Search on: MITOGEN-ACTIVATED PROTEIN KINASE 8 
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Descriptor English:   Mitogen-Activated Protein Kinase 8 
Descriptor Spanish:   Proteína Quinasa 8 Activada por Mitógenos 
Descriptor Portuguese:   Proteína Quinase 8 Ativada por Mitógeno 
Tree Number:   D08.811.913.696.620.682.700.567.374.500
D12.644.360.450.340.500
D12.776.476.450.340.500
Definition English:   A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 43 and 48 KD exist due to multiple ALTERNATIVE SPLICING. 
History Note English:   2005(2000) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38732 
Unique Identifier:   D048055 

Occurrence in VHL:
 

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